Bent had been ruled out of England's postponed match with Holland on Wednesday but is set to line up at Craven Cottage on Saturday.
The forward scored nine goals in 16 matches after his club record ?18million move from Sunderland in January and established himself as a first-choice player for his country.
Shouldering the responsibility: Darren Bent (left) can lead Aston Villa's line
Villa boss Alex McLeish has almost a clean bill of health for his first competitive game in charge since replacing Gerard Houllier in June.
Central defender James Collins has also overcome the back injury which prompted his withdrawal from the Welsh squad to face Australia in midweek.
Midfielder Fabian Delph is also in contention after a series of injury setbacks during the past two years, including ankle surgery at the end of last season.
Fighting fit: James Collins (left) is set to take his place in the Aston Villa side
McLeish said: 'At this moment there are no injuries to shout about. We have almost everyone available. There is no-one on the treatment table.
'Bent is fine with his shoulder. Collins was struggling with his back but the doctor injected him and took some blood out of a lump at the base of his back.
'He was in a lot of discomfort and it was right he should pull out of the midweek game for his country. But we believe he will be ready for the weekend.'
Defender Carlos Cuellar (knee) is the only absentee through injury.
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Source: Daily Mail
Source: Daily Mail